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From the BBC World Service, listen now by searching for the explanation wherever you get your BBC podcasts.
Hello, and welcome to the conversation, the show that takes you around the world through the stories of extraordinary women.
I am Beatriz de la Pabak.
Now, we all know that the problems caused by substance misuse and the trade in illicit drugs are vast and complex.
And today im joined by two women addressing some of these issues at a local and national level.
They are Angela Koenicke, who is a journalist in the United States and lost her 21 year old daughter to fentanyl poisoning.
Angela has since founded Emilys Hope, a non profit organization to raise awareness in the opioid crisis and end stigma of addiction.
And my second guest is Laura da Rigo.
She works in Paris as diplomatic advisor at the Inter ministerial mission on combating drugs and addictive behaviors.
They provide independent scientific evidence and analysis on different drug issues.
She's also chaired the management board of the European Monitoring center on Drugs and Drug Addiction, the only woman to hold the role.
Shes speaking to us today in a personal capacity.
Angela, Laura, welcome to the conversation.
Thank you very much.
Im very grateful to be here as well.
Laura, you speak with experts and representatives from all over France and Europe about the issues surrounding the illicit drug trade and drug addiction.
Whats the scale of the problem?