2025-02-26
1 小时 59 分钟Hello boys and girls, ladies and germs, this is Tim Ferriss.
Welcome to another and very detailed, very practical episode of the Tim Ferriss show.
My guest today is Dr. Keith Barr.
He is a professor at the University of California, Davis in the Department of Physiology and Membrane Biology.
We get into so many facets of exercise, what you can use today that is counterintuitive.
I had my mind blown.
I took so many notes.
We talked about isometric exercise for tendon health, optimizing different protocols, debunking on some level eccentric training specifically for connective tissue, how to load post injury or surgery, collagen supplementation, things like BPC157, pharmaceutical impacts on tendons, estrogen's role in tendon health and strength, mitochondria, ketogenic diet, longevity, inflammation.
And taking a balanced perspective on all of these things, how do you use them?
We get into exact training protocols that rock climbers use.
It is an amazing episode and that's not because of me, it's because of Keith.
So let me give you a quick bio and then we'll hop right into it.
During his PhD studies, his research revealed that the mechanical strain on muscle fibers activates the mammalian target of rapamycin.
Some of you may know that as mtor signaling pathway, a crucial regulator of muscular hypertrophy or muscle growth.
So he knows a lot about muscle growth.
He's been a strength training coach as well.
Subsequently he studied the molecular dynamics of skeletal muscle adaptation to endurance training under the guidance of Dr. John Halazzi, a legend in the field of exercise physiology, considered the father of modern exercise biochemistry.
Building on all of this, he conducted research into tendon health and the potential for engineering ligaments, that is creating ligaments in the lab upon which he can test all sorts of things which could also have implications for treatment and recovery from injuries.
Dr. Barr now runs the Functional Molecular Biology Lab at UC Davis.
His labs work work ranges from studying molecular changes in our cells to conducting studies to affect real world improvements in people's health, longevity and quality of life.