The Life Scientific - Ijeoma Uchegbu

《科学的生命——伊洁玛·乌切古布》

Discovery

科学

2025-03-04

26 分钟
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Imagine a nanoparticle, less that a thousandth of the width of a human hair, that is so precise that it can carry a medicine to just where it’s needed in the body, improving the drug’s impact and reducing side effects. Ijeoma Uchegbu, Professor of Pharmaceutical Nanoscience at University College London, has spent her career with this goal in mind. She creates nanoparticles to carry medicines to regions of the body that are notoriously hard to reach, such as the back of the eye and the brain. With clinical trials in the pipeline, she hopes to treat blindness with eyedrops, transform pain relief and tackle the opioid crisis. Ijeoma took an unconventional route into science. Growing up in the UK and in Nigeria, she tells Professor Jim Al-Khalili her remarkable life story, from being fostered by a white family in rural Kent, while her Nigerian parents finished their studies, to struggling to pay the bills through her PhD as a single mum with young children. So passionate is Ijeoma to spread her love of science, she’s even turned to stand-up comedy to help get her message across!
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  • Imagine for a moment a particle on the nanoscale less

  • than a thousandth of the width of a human hair that operates

  • with such precision that it can carry a medicine to a specific site in the body

  • and release it just where it's needed,

  • improving the drug's impact and reducing side effects.

  • This idea has inspired and driven the research of my guest today.

  • Ijeoma Uchebu is Professor of Pharmaceutical Nanoscience at University College London.

  • She uses the nanoparticles she's created to carry medicines

  • to regions of the body that are notoriously hard to reach.

  • The back of the eye and the brain.

  • With clinical trials in the pipeline, her hope is to treat blindness with eye drops,

  • transform pain relief and address the opioid crisis.

  • Ijeoma grew up in the UK and in Nigeria and took an unconventional route to becoming a scientist.

  • A single mother with three small children trying to make ends meet.

  • She might have given up on the idea, but she didn't.

  • In fact,

  • she's had an illustrious scientific career

  • and in October she takes up the role of President of Wolfson College at Cambridge University.

  • And her passion for science and sharing it with others is as strong as ever.

  • She's even turned to stand up comedy to help get her message across.