How David Fajgenbaum saved his own life — and thousands of others

大卫·法金鲍姆如何拯救了自己的生命——以及成千上万的人

WorkLife with Adam Grant

商务

2025-03-25

40 分钟
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David Fajgenbaum had his last rites read to him at 25 years old after a brutal struggle with an inflammatory disease that attacks the vital organs. As a medical student with two weeks left to live, he repurposed a drug and tested it on himself—and saved his own life. Now, he’s repeating the same process for many others through his nonprofit, Every Cure, with the mission of unlocking the full potential of existing drugs to treat every disease possible. David and Adam discuss the building blocks of resilience, explore the disincentives that prevent hidden cures from coming to light, and explain how AI is aiding creative discovery to save lives.  Follow Host: Adam Grant (Instagram | LinkedIn | Website) Guest: David Fajgenbaum (Instagram | LinkedIn)  Links https://everycure.org/ Subscribe to TED  Instagram: @ted YouTube: @TED TikTok: @tedtoks LinkedIn: @ted-conferences Website: ted.com Podcasts: ted.com/podcasts For the full text transcript, visit ted.com/podcasts/rethinking-with-adam-grant-transcripts Hosted on Acast. See acast.com/privacy for more information.
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  • I've got this vision for the future.

  • I've got the people I love by my side.

  • And then I'm going to take it one breath at a time.

  • Hey, everyone, it's Adam Grant.

  • Welcome back to Rethinking my podcast on the science of what makes us tick with the TED Audio Collective.

  • I'm an organizational psychologist,

  • and I'm taking you inside the minds of fascinating people to explore new thoughts and new ways of thinking.

  • My guest today is David Fagenbaum.

  • I've never met a more inspiring person.

  • David's a physician scientist at Penn who saved his own life by repurposing a drug and testing it on himself.

  • Now his non profit, EveryCure, has used that method to save thousands of others.

  • I think that most physicians and researchers,

  • they hear about a drug and they will say that is a diabetes drug.

  • Well, no, it's not a diabetes drug.

  • It is a drug that modulates this pathway and it has an effect in diabetes,

  • and it also could have an effect in all these other things.

  • AI is central to David's work,

  • and it's hard to think of a more exciting use case for this technology.

  • Just knowing he exists gives me hope, and I think he'll have the same effect on you.

  • David, welcome to Rethinking.